Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871423 | 0.84 | KDM4E (0.58) | ADORA1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11253837 | 0.84 | ALDH1A1 (0.43) | ADORA1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11480918 | 0.76 | ADORA1 (0.45) | ADORA1KDM4EALDH1A1GAAHPGD | |
| SCHEMBL5872072 | 0.75 | KDM4E (0.60) | KDM4EMEN1KMT2APKMPOLB | |
| SCHEMBL4185653 | 0.75 | MAT2A (0.56) | ADORA1KDM4ELMNAKMT2APOLB | |
| SCHEMBL6225951 | 0.74 | ADORA1 (0.52) | ADORA1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL157878 | 0.74 | ADORA1 (0.52) | ADORA1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL28307054 | 0.73 | KDM4E (0.67) | KDM4ELMNAMEN1KMT2APKM | |
| SCHEMBL11484356 | 0.73 | MEN1 (0.49) | ADORA1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL11486400 | 0.73 | ADORA1 (0.45) | ADORA1KDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4215123-A | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-29 | — | — | US | claimed |
| CN-120136886-A | PDE4 inhibitor with pyranonaphthyridone skeleton and preparation method and application thereof | 中山大学 | 2025-06-13 | — | — | CN | disclosed |
| US-4215123-A | Antisecretory 4-oxy-3-carboxy or cyano-1,2-dihydro-2-oxo-1,8-naphthyridine derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-07-29 | — | — | US | disclosed |