Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.42 |
| ▸ | MEN1 | O00255 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490047 | 0.75 | SIGMAR1 (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11494201 | 0.74 | CNR2 (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| Propane SCHEMBL11495361 | 0.74 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11539640 | 0.72 | CNR2 (0.50) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11496730 | 0.70 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL11491368 | 0.66 | HPGD (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL442022 | 0.65 | CA12 (0.52) | ALDH1A1SMN1; SMN2LMNAHTTGAA | |
| SCHEMBL25555106 | 0.65 | ALDH1A1 (0.73) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7109342 | 0.65 | MEN1 (0.49) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL20432050 | 0.64 | CCR1 (0.40) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202832-A | ANTILIPEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |