Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11494201 | 0.87 | CNR2 (0.46) | SIGMAR1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL11490044 | 0.86 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL11491368 | 0.83 | HPGD (0.49) | SIGMAR1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11490146 | 0.81 | HTT (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11495724 | 0.81 | USP2 (0.51) | SIGMAR1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11496730 | 0.81 | ALDH1A1 (0.43) | SIGMAR1MEN1KMT2AALDH1A1POLB | |
| SCHEMBL11490100 | 0.81 | POLB (0.53) | MEN1KMT2APOLBLMNACYP2C9 | |
| SCHEMBL8987627 | 0.79 | CYP2C9 (0.47) | SIGMAR1ALDH1A1CYP2C9CYP2C19TMEM97 | |
| SCHEMBL8987690 | 0.76 | TMEM97 (0.59) | SIGMAR1ALDH1A1CYP2C9CYP2C19TMEM97 | |
| SCHEMBL11493896 | 0.75 | KMT2A (0.42) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202832-A | ANTILIPEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |