SCHEMBL11495477

SCHEMBL11495477

CCC1CCCC(C(=O)O)=C1N

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.37
NOS1 P29475 2/20 0.37
NOS2 P35228 2/20 0.37
ALDH1A1 P00352 1/20 0.34
OAT P04181 1/20 0.33
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
OPRK1 P41145 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4026489 0.89 HCAR2 (0.33) NOS3NOS1NOS2ALDH1A1
SCHEMBL11641776 0.78 NOS1 (0.41) NOS3NOS1NOS2ALDH1A1OAT
SCHEMBL8480125 0.76 NPC1 (0.35) NOS3NOS1NOS2ALDH1A1HTT
SCHEMBL11624796 0.75 PDE9A (0.36) ALDH1A1
SCHEMBL11533490 0.71 OAT (0.33) OAT
SCHEMBL28306855 0.71 FFAR1 (0.30)
SCHEMBL17074436 0.70 P2RX7 (0.31) ALDH1A1
Bicarbonate SCHEMBL5440901 0.69 PTGS1 (0.46) ALDH1A1PTGS1PTGS2OPRK1HTT
SCHEMBL6120984 0.67 ALDH1A1 (0.42) ALDH1A1KMT2A
Propane SCHEMBL1984331 0.67 FFAR3 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4182623-A HERBICIDES, PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1980-01-08 US disclosed