Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492906 | 0.96 | DRD2 (0.47) | FDPSDRD2DRD3DRD4GAA | |
| SCHEMBL11492631 | 0.94 | DRD2 (0.46) | FDPSDRD2DRD3DRD4SIGMAR1 | |
| SCHEMBL11493582 | 0.91 | DRD2 (0.47) | FDPSDRD2DRD3DRD4GAA | |
| SCHEMBL11492540 | 0.87 | KCNH2 (0.44) | — | |
| SCHEMBL11489578 | 0.87 | ICMT (0.36) | FDPS | |
| SCHEMBL11496329 | 0.86 | SIGMAR1 (0.50) | HPGDSIGMAR1 | |
| SCHEMBL11494126 | 0.83 | KCNH2 (0.47) | — | |
| SCHEMBL11493895 | 0.83 | ICMT (0.41) | DRD2DRD3DRD4HPGDSIGMAR1 | |
| SCHEMBL11489231 | 0.82 | ICMT (0.43) | HPGD | |
| SCHEMBL11496271 | 0.82 | KCNH2 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |