Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 16/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115096 | 0.86 | KDM4E (0.36) | METAP2CYP1A2 | |
| SCHEMBL114970 | 0.84 | CASR (0.34) | ESR1ESR2 | |
| SCHEMBL115974 | 0.82 | METAP2 (0.42) | METAP2ESR1ESR2 | |
| SCHEMBL114962 | 0.82 | SMN1; SMN2 (0.34) | ESR1ESR2 | |
| SCHEMBL115067 | 0.81 | BRD4 (0.40) | TACR1 | |
| SCHEMBL116024 | 0.80 | METAP2 (0.39) | METAP2ESR1ESR2TACR1 | |
| SCHEMBL116023 | 0.78 | METAP2 (0.40) | METAP2ESR1ESR2CYP17A1CYP1A2 | |
| SCHEMBL115108 | 0.76 | METAP2 (0.43) | METAP2GRM2 | |
| SCHEMBL113625 | 0.76 | METAP2 (0.41) | METAP2ESR1ESR2 | |
| SCHEMBL115026 | 0.75 | GAA (0.42) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | METAP2 2747/4885ESR1 4164/4885ESR2 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.