Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GGT1 | P19440 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | OTC | P00480 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144726 | 0.95 | GGT1 (0.40) | NOD1MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL7028708 | 0.93 | NOD1 (0.53) | NOD1FOLH1TLR2 | |
| SCHEMBL19506115 | 0.93 | PRMT1 (0.45) | NOD1MEN1KMT2ACYP1A2SMN1; SMN2 | |
| SCHEMBL7029218 | 0.93 | NOD1 (0.53) | NOD1FOLH1TLR2 | |
| SCHEMBL8664762 | 0.93 | NOD1 (0.53) | NOD1FOLH1TLR2 | |
| SCHEMBL25334014 | 0.93 | NOD1 (0.53) | NOD1FOLH1TLR2 | |
| SCHEMBL7029222 | 0.93 | NOD1 (0.53) | NOD1FOLH1TLR2 | |
| SCHEMBL8664765 | 0.93 | NOD1 (0.53) | NOD1FOLH1TLR2 | |
| SCHEMBL7028702 | 0.93 | NOD1 (0.53) | NOD1FOLH1TLR2 | |
| SCHEMBL31078268 | 0.93 | NOD1 (0.53) | NOD1FOLH1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2259768-B1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | MERCK PATENT GMBH (DE) | 2019-05-22 | — | — | EP | disclosed |
| US-10278911-B2 | Compositions containing cyclic peptides and methods of use | MERCK PATENT GMBH (DE) | 2019-05-07 | — | — | US | disclosed |
| US-20150265516-A1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20110027209-A1 | Compositions Containing Cyclic Peptides And Methods Of Use | MERCK PATENT GESELLSCHAFT (DE) | 2011-02-03 | — | — | US | disclosed |
| EP-2259768-A1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | Merck Patent GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009124754-A1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | MERCK PATENT GMBH (DE) | 2009-10-15 | — | — | WO | disclosed |
| WO-1995007294-A1 | PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS | SCIOS NOVA INC. (US) | 1995-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150265516-A1 | COMPOSITIONS CONTAINING CYCLIC PEPTIDES AND METHODS OF USE | CUTA, NGLY1, CALCA | NOD1 3795/4885MEN1 1564/4885KMT2A 4725/4885 |
| US-10278911-B2 | Compositions containing cyclic peptides and methods of use | CUTA, NGLY1, CALCA | NOD1 3795/4885MEN1 1564/4885KMT2A 4725/4885 |
| US-20110027209-A1 | Compositions Containing Cyclic Peptides And Methods Of Use | CUTA, NGLY1, CALCA | NOD1 3795/4885MEN1 1564/4885KMT2A 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.