Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.50 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.50 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28299500 | 0.81 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2 | |
| SCHEMBL11865449 | 0.80 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2 | |
| SCHEMBL11801720 | 0.78 | SPHK2 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2 | |
| SCHEMBL11868109 | 0.77 | TUBB4A (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2 | |
| SCHEMBL11810462 | 0.77 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2 | |
| Lobendazole SCHEMBL205437 | 0.76 | LMNA (0.64) | NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2 | |
| Lobendazole SCHEMBL29682294 | 0.76 | LMNA (0.64) | NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2 | |
| SCHEMBL6704028 | 0.76 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2 | |
| Carbendazim SCHEMBL21051 | 0.76 | LMNA (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| Carbendazim SCHEMBL29357746 | 0.76 | LMNA (0.71) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55162708-A | — | — | None | — | — | JP | disclosed |
| JP-S55162708-A | FUNGICIDE FOR AGRICULTURE AND GARDENING | HOKKO CHEM IND CO LTD | 1980-12-18 | — | — | JP | disclosed |