SCHEMBL28299500

SCHEMBL28299500

CCCCNC(=O)OC(=O)Nc1nc2ccccc2[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.61
RAB9A P51151 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
ALDH1A1 P00352 3/20 0.61
SPHK2 Q9NRA0 1/20 0.60
SPHK1 Q9NYA1 1/20 0.60
BCHE P06276 2/20 0.59
TRPC3 Q13507 1/20 0.59
TRPC4 Q9UBN4 1/20 0.59
TRPC5 Q9UL62 1/20 0.59
LMNA P02545 2/20 0.54
CYP3A4 P08684 1/20 0.51
PKM P14618 1/20 0.51
KLF5 Q13887 1/20 0.51
TUBB4A P04350 1/20 0.51
CYP1A2 P05177 1/20 0.51
TUBB P07437 1/20 0.51
TUBA3C P0DPH7 1/20 0.51
CYP2D6 P10635 1/20 0.51
TSHR P16473 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27783801 0.91 RAB9A (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL9721993 0.85 NPC1 (0.61) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL11742917 0.85 NPC1 (0.67) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL11865449 0.81 NPC1 (0.65) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL11499486 0.81 NPC1 (0.59) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL11810462 0.81 NPC1 (0.58) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL5973026 0.81 LMNA (0.69) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL11703652 0.81 SPHK2 (0.70) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL3715154 0.81 ALDH1A1 (0.47) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2
SCHEMBL21614331 0.80 BCHE (0.64) NPC1RAB9ASMN1; SMN2ALDH1A1SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790338-A Composition for thermoplastic elastomer 住友化学株式会社 2019-05-21 CN disclosed