SCHEMBL11501002

SCHEMBL11501002

CC(=O)CC(=O)OS(=O)(=O)c1ccccc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.43
CA9 Q16790 5/20 0.42
CA1 P00915 5/20 0.42
CA2 P00918 5/20 0.42
CA5A P35218 2/20 0.42
CA12 O43570 1/20 0.42
CYP2C9 P11712 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
KYNU Q16719 2/20 0.41
F2 P00734 2/20 0.39
HTR6 P50406 1/20 0.39
ALDH1A1 P00352 2/20 0.38
HSD17B10 Q99714 2/20 0.38
CFTR P13569 1/20 0.38
POLB P06746 1/20 0.37
MGAM O43451 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11500845 0.84 NSD2 (0.36) GAACA9CA1CA2CA5A
SCHEMBL27588754 0.78 ALDH1A1 (0.43) GAACA9CA1CA2CA5A
SCHEMBL11500997 0.77 CA12 (0.35) GAACA9CA1CA2CA12
SCHEMBL28278748 0.77 ALDH1A1 (0.43) GAAALDH1A1POLBMGAMSI
SCHEMBL11035463 0.75 ALDH1A1 (0.40) GAACA9CA1CA2CA12
SCHEMBL11037152 0.74 TSHR (0.49) GAACA9CA1CA2CA12
SCHEMBL11235235 0.74 PKM (0.53) GAACA1CA2F2ALDH1A1
SCHEMBL11225451 0.74 PKM (0.45) GAACA1CA2F2ALDH1A1
SCHEMBL27548548 0.73 GAA (0.44) GAACA9CA1CA2CA5A
Acetoacetic Acid SCHEMBL11501001 0.73 KYNU (0.45) GAACA9CA1CA2CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4225492-A Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines CASSELLA AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
US-4143033-A WATER-SOLUBLE DISAZO DYESTUFFS CONTAINING A 2-PHENYL-BENZIMIDAZOLYL,-BENZOXAZOLYL OR-BENZTHIAZOLYL MIDDLE COMPONENT CASSELLA AKTIENGESELLSCHAFT (DE) 1979-03-06 US disclosed
US-4137228-A HIGH TINCTORIAL STRENGTH, COLORFASTNESS CASSELLA AKTIENGESELLSCHAFT (DE) 1979-01-30 US disclosed