Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560757 | 0.75 | CA1 (0.42) | STAT3CTDSP1SIRT5LMNACA12 | |
| SCHEMBL9838573 | 0.74 | HSP90AB1 (0.43) | LMNACHRNA7KMT2AALDH1A1HSD11B1 | |
| SCHEMBL24951911 | 0.74 | CA12 (0.45) | STAT3CTDSP1SIRT5LMNACA12 | |
| SCHEMBL9838536 | 0.73 | TAAR1 (0.53) | CHRNA7KMT2AHSP90AB1MEN1POLB | |
| SCHEMBL15227216 | 0.72 | LMNA (0.51) | STAT3CTDSP1SIRT5LMNAHTT | |
| SCHEMBL241884 | 0.72 | CA1 (0.52) | STAT3LMNAHTTCA12CA1 | |
| SCHEMBL28774223 | 0.71 | MEN1 (0.46) | STAT3CTDSP1SIRT5LMNACA12 | |
| SCHEMBL16619075 | 0.71 | CA12 (0.39) | STAT3CTDSP1SIRT5HTTCA12 | |
| SCHEMBL18289524 | 0.71 | CA1 (0.50) | STAT3CA12CA1CA9KMT2A | |
| SCHEMBL6906905 | 0.71 | CA1 (0.50) | STAT3CA12CA1CA9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4192818-A | ANTIDEPRESSANTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1980-03-11 | — | — | US | disclosed |