Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406187 | 0.89 | ALDH1A1 (0.48) | PYCR1TSHRALDH1A1ALOX15DHFR | |
| SCHEMBL10795320 | 0.89 | PYCR1 (0.56) | PYCR1ALDH1A1DHFRADRA2AADRA2B | |
| SCHEMBL15336561 | 0.89 | APP (0.44) | PYCR1TSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL21021269 | 0.89 | APP (0.44) | PYCR1DHFRSMN1; SMN2ADRA2AADRA2B | |
| SCHEMBL1257194 | 0.88 | CA12 (0.42) | PYCR1TSHRDHFRSMN1; SMN2 | |
| SCHEMBL9512904 | 0.87 | GAA (0.40) | PYCR1TSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL1083024 | 0.85 | GAA (0.39) | PYCR1TSHRDHFRCASRGAA | |
| SCHEMBL4075155 | 0.84 | CHRM5 (0.48) | PYCR1ALOX15SMN1; SMN2CHKA | |
| SCHEMBL3290812 | 0.84 | PYCR1 (0.35) | PYCR1DHFR | |
| SCHEMBL19696453 | 0.84 | HPGD (0.53) | TSHRALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241661-A | BY COATING WITH AN ANTIOXIDANT TO DECREASE OXIDATIVE HARDENING | HERCULES INCORPORATED (US) | 1980-12-30 | — | — | US | disclosed |