Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501045 | 0.87 | PYCR1 (0.41) | GAAADRA2AADRA2BADRA2CPYCR1 | |
| SCHEMBL1083024 | 0.86 | GAA (0.39) | GAAADRA2AADRA2BADRA2CPYCR1 | |
| SCHEMBL15336561 | 0.78 | APP (0.44) | GAAPYCR1MAPTNPC1RAB9A | |
| SCHEMBL21021269 | 0.78 | APP (0.44) | ADRA2AADRA2BADRA2CPYCR1SMN1; SMN2 | |
| SCHEMBL11406187 | 0.78 | ALDH1A1 (0.48) | GAAADRA2AADRA2BADRA2CPYCR1 | |
| SCHEMBL10795320 | 0.78 | PYCR1 (0.56) | ADRA2AADRA2BADRA2CPYCR1MAPT | |
| SCHEMBL1257194 | 0.77 | CA12 (0.42) | PYCR1KMT2ASMN1; SMN2CYP1A2DHFR | |
| SCHEMBL21242338 | 0.77 | MAPT (0.35) | GAAADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL9847486 | 0.74 | GAA (0.39) | GAAADRA2AADRA2BADRA2CMAPT | |
| SCHEMBL9514288 | 0.74 | ADRA2A (0.59) | GAAADRA2AADRA2BADRA2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273418-B1 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MFG CO LTD (JP) | 1993-11-24 | — | — | EP | disclosed |
| US-4803193-A | COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0273418-A2 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |