SCHEMBL4075155

SCHEMBL4075155

C=CCN(C)c1ccncc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 1/20 0.48
CHKA P35790 1/20 0.48
SLC6A2 P23975 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
RAB9A P51151 1/20 0.38
HBB P68871 1/20 0.38
KMT2A Q03164 1/20 0.38
PYCR1 P32322 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11501045 0.84 PYCR1 (0.41) CHKASMN1; SMN2ALOX15PYCR1
SCHEMBL1257194 0.78 CA12 (0.42) SMN1; SMN2MEN1KMT2APYCR1
SCHEMBL418658 0.78 CHKA (0.46) CHRM5CHKASLC6A2SMN1; SMN2MAPT
SCHEMBL14415500 0.77 CHRNB2 (0.42)
SCHEMBL15590642 0.76 CHRM5 (0.41) CHRM5CHKASLC6A2SMN1; SMN2MAPT
SCHEMBL2103019 0.76 CHRM5 (0.54) CHRM5CHKASLC6A2SMN1; SMN2MAPT
SCHEMBL11406187 0.75 ALDH1A1 (0.48) MAPTMEN1ALOX15KMT2APYCR1
SCHEMBL3290812 0.75 PYCR1 (0.35) PYCR1
SCHEMBL21021269 0.75 APP (0.44) SLC6A2SMN1; SMN2PYCR1
SCHEMBL15336561 0.75 APP (0.44) MAPTMEN1NPC1ALOX15RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511303-A4 AMINOPYRIDYL SILANES AND SILOXANES 1993-09-01 EP claimed
US-5194555-A Incorporating dialkylaminopyridine functionality; catalyst for acylation, polymerization, reduction, oxidation INDIANA UNIVERSITY FOUNDATION (US) 1993-03-16 US claimed
EP-0511303-A1 AMINOPYRIDYL SILANES AND SILOXANES INDIANA UNIVERSITY FOUNDATION (US) 1992-11-04 EP claimed
WO-1991010714-A1 AMINOPYRIDYL SILANES AND SILOXANES INDIANA UNIVERSITY FOUNDATION (US) 1991-07-25 WO claimed
US-20090082588-A1 Process for producing fluorinated carbamates and isocyanates REPSOL YPF, S.A. (ES) 2009-03-26 US disclosed
US-20090082588-A1 Process for producing fluorinated carbamates and isocyanates REPSOL YPF, S.A. (ES) 2009-03-26 US disclosed
US-20090082588-A1 Process for producing fluorinated carbamates and isocyanates REPSOL YPF, S.A. (ES) 2009-03-26 US disclosed
EP-2036884-A1 Process for producing fluorinated isocyanates and carbamates REPSOL YPF S.A. (ES) 2009-03-18 EP disclosed
EP-2036884-A1 Process for producing fluorinated isocyanates and carbamates REPSOL YPF S.A. (ES) 2009-03-18 EP disclosed
US-5461020-A Dialkyl amino pyridine catalysts which are bound to inorganic matrices and processes for their preparation OLIN CORPORATION (US) 1995-10-24 US disclosed
EP-0607129-B1 METHYLPIPERAZINOAZEPINE DERIVATIVES, THEIR PREPARATION AND USE THERABEL RESEARCH SA (BE) 1995-08-23 EP disclosed
US-5442106-A Hydrolyzing activated ester in aqueous medium with selective catalyst INDIANA UNIVERSITY FOUNDATION (US) 1995-08-15 US disclosed
US-5393752-A Psycholigical disorders THERABEL RESEARCH S.A./N.V. (BE) 1995-02-28 US disclosed
EP-0511303-A4 AMINOPYRIDYL SILANES AND SILOXANES 1993-09-01 EP disclosed
WO-1993008150-A1 HYDROLYZING ESTERS USING 4-AMINOPYRIDYL SILOXANE CATALYSTS INDIANA UNIVERSITY FOUNDATION (US) 1993-04-29 WO disclosed
US-5194555-A Incorporating dialkylaminopyridine functionality; catalyst for acylation, polymerization, reduction, oxidation INDIANA UNIVERSITY FOUNDATION (US) 1993-03-16 US disclosed
EP-0511303-A1 AMINOPYRIDYL SILANES AND SILOXANES INDIANA UNIVERSITY FOUNDATION (US) 1992-11-04 EP disclosed
WO-1991010714-A1 AMINOPYRIDYL SILANES AND SILOXANES INDIANA UNIVERSITY FOUNDATION (US) 1991-07-25 WO disclosed
US-4997944-A Catalysts, polymer precursor INDIANA UNIVERSITY FOUNDATION (US) 1991-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090082588-A1 Process for producing fluorinated carbamates and isocyanates SRM, CA4, PRMT3 CHRM5 1816/4885CHKA 338/4885SLC6A2 3817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.