Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191128 | 0.91 | LMNA (0.51) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL8117430 | 0.90 | CYP4F2 (0.48) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL11784914 | 0.86 | LMNA (0.56) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL28537883 | 0.84 | CA12 (0.62) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL10082826 | 0.83 | LMNA (0.53) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL9357034 | 0.83 | ALDH1A1 (0.48) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL11032684 | 0.82 | TSHR (0.48) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL14465366 | 0.82 | LMNA (0.51) | LMNACYP1A2CYP3A4MAOAALDH1A1 | |
| SCHEMBL240794 | 0.81 | GABRP (0.59) | CYP3A4ALDH1A1HSD17B10MAPTGAA | |
| SCHEMBL31117550 | 0.81 | GABRP (0.59) | CYP3A4ALDH1A1HSD17B10MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352677-A | Antihyperlipidemic agents | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0407200-B1 | Cinnamamide derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 1994-06-01 | — | — | EP | disclosed |
| US-5294643-A | Cinnamamide derivative | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI (JP) | 1994-03-15 | — | — | US | disclosed |
| US-5294624-A | Antiartheriosclerosis | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0407200-A1 | Cinnamamide derivatives | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-01-09 | — | — | EP | disclosed |