Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP8 | P22894 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 2/20 | 0.35 |
| ▸ | MMP14 | P50281 | 2/20 | 0.35 |
| ▸ | MMP16 | P51512 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10864166 | 0.83 | POLB (0.43) | POLBGAAGFERESR1HTR6 | |
| SCHEMBL7113719 | 0.78 | ABL1 (0.39) | POLBGAAGFERESR1MMP9 | |
| SCHEMBL6899092 | 0.76 | POLB (0.54) | POLBGAAGFERHTR6KMT2A | |
| SCHEMBL9793431 | 0.74 | HTR6 (0.62) | POLBGAAGFERHTR6KMT2A | |
| SCHEMBL1028866 | 0.74 | POLB (0.49) | POLBGAAGFERHTR6KMT2A | |
| SCHEMBL11264693 | 0.73 | GAA (0.57) | POLBGAAGFERESR1HTR6 | |
| SCHEMBL13241419 | 0.72 | ALDH1A1 (0.56) | POLBGAAKMT2ATDP1STAT3 | |
| SCHEMBL10864169 | 0.72 | POLB (0.55) | POLBGAAGFERESR1HTR6 | |
| SCHEMBL6687729 | 0.72 | POLB (0.46) | POLBGAAGFERKMT2AHTT | |
| Phenol SCHEMBL6905378 | 0.71 | HTR6 (0.62) | POLBGAAGFERESR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010595-A1 | Bis(4-hydroxyphenylthiophenyl)biphenyldisulphones and bis(4-hydroxyphenyl-sulphonylphenyl)-biphenyldisulphones, their preparation and their use | Mobay Chemical Corporation (US) | 1980-05-14 | — | — | EP | disclosed |