Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 5/20 | 0.43 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | MMP8 | P22894 | 5/20 | 0.43 |
| ▸ | MMP12 | P39900 | 5/20 | 0.43 |
| ▸ | MMP13 | P45452 | 5/20 | 0.43 |
| ▸ | MMP14 | P50281 | 5/20 | 0.43 |
| ▸ | MMP16 | P51512 | 5/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | UQCRB | P14927 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10864169 | 0.86 | POLB (0.55) | POLBGAAGFERESR1HNF4A | |
| SCHEMBL11501339 | 0.83 | POLB (0.44) | POLBGAAGFERMMP1MMP2 | |
| SCHEMBL1028866 | 0.82 | POLB (0.49) | POLBGAAGFERMMP1MMP2 | |
| SCHEMBL6899092 | 0.81 | POLB (0.54) | POLBGAAGFERMMP1MMP2 | |
| SCHEMBL28348378 | 0.78 | HNF4A (0.49) | POLBGAAGFERMMP1MMP2 | |
| SCHEMBL29700218 | 0.78 | HNF4A (0.49) | POLBGAAGFERMMP1MMP2 | |
| SCHEMBL6687729 | 0.77 | POLB (0.46) | POLBGAAGFERMMP1MMP2 | |
| SCHEMBL9242466 | 0.75 | HTR6 (0.55) | POLBGAAGFERMMP1MMP2 | |
| SCHEMBL11264693 | 0.75 | GAA (0.57) | POLBGAAGFERMMP1MMP2 | |
| SCHEMBL4734126 | 0.73 | MMP2 (0.46) | GAAMMP1MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170986-A2 | A process for the preparation of copolycarbonates of sulfonyl diphenol | MOBAY CORPORATION (US) | 1986-02-12 | — | — | EP | disclosed |
| US-4535143-A | QUATERNARY SALTS AND TERTIARY AMINE CATALYSTS; NONEMULSIFICATION MOLECULAR WEIGHT CONTROL, PROCESS | MOBAY CHEMICAL CORPORATION (US) | 1985-08-13 | — | — | US | disclosed |
| US-4303776-A | Bis(4-hydroxyphenyl sulfonylphenyl) bisphenyl disulfones and useful resins based thereon | MOBAY CHEMICAL CORPORATION (US) | 1981-12-01 | — | — | US | disclosed |
| US-4303776-A | Bis(4-hydroxyphenyl sulfonylphenyl) bisphenyl disulfones and useful resins based thereon | MOBAY CHEMICAL CORPORATION (US) | 1981-12-01 | — | — | US | disclosed |
| EP-0010595-A1 | Bis(4-hydroxyphenylthiophenyl)biphenyldisulphones and bis(4-hydroxyphenyl-sulphonylphenyl)-biphenyldisulphones, their preparation and their use | Mobay Chemical Corporation (US) | 1980-05-14 | — | — | EP | disclosed |