Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | CD40 | P25942 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501388 | 0.82 | MEN1 (0.44) | ALDH1A1TTRFABP4CCNA2CDK2 | |
| SCHEMBL10823511 | 0.77 | TTR (0.44) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11425182 | 0.77 | MAPT (0.57) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11344808 | 0.76 | MAPK14 (0.43) | ALDH1A1TTRFABP4CCNA2CDK2 | |
| SCHEMBL11425185 | 0.75 | KCNMA1 (0.46) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10823618 | 0.73 | TTR (0.39) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10907645 | 0.72 | CD40 (0.43) | ALDH1A1TTRFABP4CCNA2CDK2 | |
| SCHEMBL11352062 | 0.72 | TIMP3 (0.47) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL11352045 | 0.71 | MEN1 (0.42) | ALDH1A1TTRFABP4CCNA2CDK2 | |
| SCHEMBL10823624 | 0.71 | IDH1 (0.53) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |