Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11501387 | 0.82 | ALDH1A1 (0.45) | MEN1KMT2ATDP1L3MBTL1MAPT | |
| SCHEMBL11425185 | 0.82 | KCNMA1 (0.46) | MEN1KMT2ATDP1NFKBIAAGTR1 | |
| SCHEMBL11425182 | 0.76 | MAPT (0.57) | MEN1KMT2ATDP1POLBMAPT | |
| SCHEMBL10628268 | 0.75 | NT5E (0.52) | MEN1KMT2ATDP1KCNMA1POLB | |
| SCHEMBL10709854 | 0.74 | TDP1 (0.46) | MEN1KMT2ATDP1POLBL3MBTL1 | |
| SCHEMBL11501439 | 0.72 | SNCA (0.50) | MEN1KMT2AKCNMA1MAPTSMN1; SMN2 | |
| SCHEMBL11430987 | 0.72 | KDR (0.40) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL10823618 | 0.72 | TTR (0.39) | MEN1KMT2ATDP1POLBMAPT | |
| SCHEMBL13588699 | 0.71 | TDP1 (0.54) | MEN1KMT2ATDP1KCNMA1POLB | |
| SCHEMBL11439481 | 0.71 | CD40 (0.68) | MEN1KMT2APOLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |