Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.38 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.32 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11419595 | 0.87 | ANPEP (0.33) | GABRR1OTCGLRA1SLC6A9OR51E2 | |
| SCHEMBL7823406 | 0.82 | — | — | |
| SCHEMBL11424753 | 0.81 | GABBR2 (0.42) | GABRR1TSHRALDH1A1GABBR2GABBR1 | |
| SCHEMBL339989 | 0.78 | — | — | |
| SCHEMBL9152811 | 0.78 | PLG (0.32) | LMNA | |
| SCHEMBL2958882 | 0.78 | GABBR2 (0.59) | GABRR1GABBR2GABBR1 | |
| Bromide SCHEMBL9159534 | 0.76 | PLG (0.31) | LMNA | |
| Bromide SCHEMBL9154886 | 0.76 | GABBR2 (0.57) | GABRR1GABBR2GABBR1 | |
| SCHEMBL2951181 | 0.73 | MMP2 (0.40) | CYP3A4ANPEPERAP2 | |
| SCHEMBL11529930 | 0.71 | TPI1 (0.30) | GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148624-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1979-04-10 | — | — | US | claimed |
| US-4233056-A | POSTEMERGENCE HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1980-11-11 | — | — | US | disclosed |
| US-4148624-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1979-04-10 | — | — | US | disclosed |
| US-4148624-A | HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1979-04-10 | — | — | US | disclosed |