Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.59 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.59 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.59 |
| ▸ | FDPS | P14324 | 3/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9154886 | 0.98 | GABBR2 (0.57) | GABBR2GABBR1GABRR1FDPSLPAR3 | |
| SCHEMBL11424753 | 0.88 | GABBR2 (0.42) | GABBR2GABBR1GABRR1FDPSLPAR3 | |
| SCHEMBL11501421 | 0.78 | GABRR1 (0.38) | GABBR2GABBR1GABRR1 | |
| SCHEMBL1315772 | 0.77 | GABBR2 (0.54) | GABBR2GABBR1GABRR1LPAR3LPAR2 | |
| SCHEMBL497185 | 0.75 | GABBR2 (0.76) | GABBR2GABBR1GABRR1FDPSLPAR3 | |
| Sgs-742 SCHEMBL195133 | 0.74 | GABBR2 (1.00) | GABBR2GABBR1GABRR1 | |
| SCHEMBL150613 | 0.73 | GABBR2 (0.73) | GABBR2GABBR1GABRR1FDPSLPAR3 | |
| SCHEMBL673048 | 0.73 | GABBR2 (0.73) | GABBR2GABBR1GABRR1FDPSLPAR3 | |
| SCHEMBL673559 | 0.73 | GABBR2 (0.73) | GABBR2GABBR1GABRR1FDPSLPAR3 | |
| SCHEMBL21082027 | 0.73 | GABBR2 (0.73) | GABBR2GABBR1GABRR1FDPSLPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402312-B1 | P-substituted propane-phosphinic acid compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | claimed |
| EP-0402312-A2 | P-substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1990-12-12 | — | — | EP | claimed |
| JP-3020288-A | — | — | None | — | — | JP | disclosed |
| US-7749985-B2 | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use | XENOPORT, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090286759-A1 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2009-11-19 | — | — | US | disclosed |
| US-7585996-B2 | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use | XENOPORT, INC. (US) | 2009-09-08 | — | — | US | disclosed |
| US-20080146526-A1 | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use | XENOPORT, INC. | 2008-06-19 | — | — | US | disclosed |
| WO-2008033572-A1 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-03-20 | — | — | WO | disclosed |
| EP-0402312-B1 | P-substituted propane-phosphinic acid compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| US-5190934-A | Treatment of cognitive and memory disorders | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| JP-H0320288-A | P-SUBSTITUTED PROPANE-PHOSPHINIC ACID COMPOUND | CIBA GEIGY AG | 1991-01-29 | — | — | JP | disclosed |
| EP-0402312-A2 | P-substituted propane-phosphinic acid compounds | CIBA-GEIGY AG (CH) | 1990-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286759-A1 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | APEH, NAPEPLD, AASDHPPT | GABBR2 804/4885GABBR1 598/4885GABRR1 1069/4885 |
| US-20080146526-A1 | Acyloxyalkyl carbamate prodrugs, methods of synthesis and use | APEH, NAPEPLD, AASDHPPT | GABBR2 804/4885GABBR1 598/4885GABRR1 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.