Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 16/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 8/20 | 0.47 |
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550870 | 0.80 | RAB9A (0.60) | MAOAMAOBMEN1NPC1MAPT | |
| SCHEMBL11555063 | 0.80 | ALDH2 (0.78) | ALDH2HRH3MAOAMAOBMEN1 | |
| SCHEMBL11558281 | 0.79 | ALDH2 (0.80) | ALDH2HRH3MAOAMAOBMEN1 | |
| SCHEMBL8983953 | 0.79 | ALDH2 (0.80) | ALDH2HRH3MAOAMAOBMEN1 | |
| SCHEMBL10999849 | 0.79 | ALDH2 (0.80) | ALDH2HRH3MAOAMAOBMEN1 | |
| SCHEMBL11556173 | 0.77 | ALDH2 (0.73) | ALDH2HRH3MAOAMAOBMEN1 | |
| SCHEMBL11875767 | 0.76 | MAPT (0.64) | ALDH2MAOAMAOBMEN1NPC1 | |
| SCHEMBL1701152 | 0.74 | ALDH2 (1.00) | ALDH2MAOAMAOB | |
| SCHEMBL8961840 | 0.74 | XDH (0.65) | MAPT | |
| SCHEMBL11501433 | 0.74 | GLA (0.77) | MAOAMAOBMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4196128-A | Process for the preparation of 3-cyanochromones | WARNER-LAMBERT COMPANY (US) | 1980-04-01 | — | — | US | disclosed |