Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | MAOA | P21397 | 7/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11551420 | 0.88 | ALDH1A1 (0.55) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11875767 | 0.83 | MAPT (0.64) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL5242883 | 0.81 | MAPT (0.59) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11501434 | 0.80 | ALDH2 (0.59) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL31619653 | 0.77 | GPR35 (0.45) | RAB9ANPC1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL5242625 | 0.77 | RAB9A (0.61) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11565649 | 0.77 | RAB9A (0.61) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL19182258 | 0.77 | ALDH1A1 (0.44) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL28990293 | 0.77 | RAB9A (0.61) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2109107 | 0.77 | RAB9A (0.61) | RAB9ANPC1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151180-A | INTERMEDIATES FOR ANTIALLERGENS, ANTIHISTAMINES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-04-24 | — | — | US | claimed |