SCHEMBL1150154

SCHEMBL1150154

CCCCOc1ccc(C[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1.Fc1c(F)c(F)c([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.43
CHRNA7 P36544 8/20 0.39
SNCA P37840 2/20 0.38
PPARG P37231 1/20 0.38
PPARD Q03181 1/20 0.38
PPARA Q07869 1/20 0.38
FAAH O00519 1/20 0.37
ITGB1 P05556 1/20 0.37
ITGA4 P13612 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1045377 0.87 LTA4H (0.50) LTA4HCHRNA7SNCAPPARGPPARD
Hydrochloric Acid SCHEMBL1046793 0.85 LTA4H (0.54) LTA4HCHRNA7SNCA
Iodide SCHEMBL1047429 0.85 LTA4H (0.54) LTA4HCHRNA7SNCA
Bromide SCHEMBL1044358 0.85 LTA4H (0.54) LTA4HCHRNA7SNCA
SCHEMBL3694644 0.84 LTA4H (0.47) LTA4HCHRNA7SNCAPPARGPPARD
SCHEMBL8372241 0.81 LTA4H (0.50) LTA4HCHRNA7SNCAPPARGPPARA
Bromide SCHEMBL5571267 0.81 LTA4H (0.55) LTA4HCHRNA7SNCA
SCHEMBL8378569 0.81 LTA4H (0.50) LTA4HCHRNA7SNCAPPARGPPARA
Acetic Acid SCHEMBL1042649 0.78 LTA4H (0.46) LTA4HPPARGPPARDPPARAFAAH
SCHEMBL3129866 0.76 LTA4H (0.47) LTA4HFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530617-B2 Silicon-containing particle, process for producing the same, organic-polymer composition, ceramic, and process for producing the same DOW CORNING TORAY COMPANY, LTD. (JP) 2013-09-10 US disclosed
US-20120121981-A1 Electrode Active Material, Electrode, And Electricity Storage Device DOW CORNING TORAY CO., LTD. (JP) 2012-05-17 US disclosed
US-20110033708-A1 Silicon-Containing Particle, Process For Producing The Same, Organic-Polymer Composition, Ceramic, And Process For Producing The Same DOW CORNING TORAY COMPANY, LTD. (JP) 2011-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110033708-A1 Silicon-Containing Particle, Process For Producing The Same, Organic-Polymer Composition, Ceramic, And Process For Producing The Same SKP1, SPOP, SSRP1 LTA4H 1815/4885CHRNA7 3393/4885SNCA 1754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.