Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685649 | 1.00 | LMNA (0.51) | LMNAALDH1A1HSD17B10TSHRTP53 | |
| SCHEMBL1150168 | 1.00 | LMNA (0.51) | LMNAALDH1A1HSD17B10TSHRTP53 | |
| SCHEMBL1150163 | 1.00 | LMNA (0.51) | LMNAALDH1A1HSD17B10TSHRTP53 | |
| SCHEMBL1685648 | 1.00 | LMNA (0.51) | LMNAALDH1A1HSD17B10TSHRTP53 | |
| SCHEMBL1149828 | 0.86 | ALDH1A1 (0.41) | LMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL1150465 | 0.85 | ALDH1A1 (0.53) | LMNAALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL1685655 | 0.84 | LMNA (0.46) | LMNAALDH1A1TSHRTP53MAPT | |
| SCHEMBL1150190 | 0.84 | LMNA (0.34) | LMNAALDH1A1HSD17B10HTT | |
| SCHEMBL1150187 | 0.83 | ALDH1A1 (0.47) | LMNAALDH1A1TSHRTP53 | |
| SCHEMBL20815360 | 0.83 | LMNA (0.45) | LMNAALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893294-B2 | Process for production of trans-2, 2-dimethyl-3-formylcyclopropanecarboxylic acid ester | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20090314987-A1 | PROCESS FOR PRODUCTION OF TRANS-2, 2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-12-24 | — | — | US | disclosed |
| EP-2053037-A1 | PROCESS FOR PRODUCTION OF TRANS-2,2-DIMETHYL- 3-FORMYLCYCLOPROPANE CARBOXYLIC ACID ESTER | Sumitomo Chemical Company, Limited (JP) | 2009-04-29 | — | — | EP | disclosed |