SCHEMBL1150190

SCHEMBL1150190

COC(=O)C1C(COC(C)=O)C1(C)C

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
ALDH1A1 P00352 3/20 0.32
HSD17B10 Q99714 1/20 0.32
POLA1 P09884 1/20 0.32
HTT P42858 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3358613 0.85 POLA1 (0.32) LMNAPOLA1HTT
SCHEMBL1685649 0.84 LMNA (0.51) LMNAALDH1A1HSD17B10HTT
SCHEMBL1150166 0.84 LMNA (0.51) LMNAALDH1A1HSD17B10HTT
SCHEMBL1150168 0.84 LMNA (0.51) LMNAALDH1A1HSD17B10HTT
SCHEMBL1685648 0.84 LMNA (0.51) LMNAALDH1A1HSD17B10HTT
SCHEMBL1150163 0.84 LMNA (0.51) LMNAALDH1A1HSD17B10HTT
SCHEMBL3361579 0.82 POLA1 (0.34) LMNAPOLA1HTT
SCHEMBL1685638 0.82 NAAA (0.35) LMNAPOLA1
SCHEMBL3357854 0.81 ALDH1A1 (0.34) LMNAALDH1A1HSD17B10
SCHEMBL10507865 0.81 ALDH1A1 (0.34) LMNAALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117263791-A Method for preparing 3, 3-dimethyl-1, 2-cyclopropane dicarboxylic acid 中国科学院大连化学物理研究所 2023-12-22 CN disclosed
EP-2341042-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND SUMITOMO CHEMICAL CO (JP) 2019-03-20 EP disclosed
CN-103958533-B Optically active bisoxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same SUMITOMO CHEMICAL CO.,LTD. (JP) 2016-02-10 CN disclosed
EP-1783111-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-04-08 EP disclosed
EP-2781522-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST Sumitomo Chemical Company, Limited (JP) 2014-09-24 EP disclosed
CN-103958533-A Optically active bis-oxazoline compound, asymmetric catalyst, and method for producing optically active cyclopropane compound using same SUMITOMO CHEMICAL CO 2014-07-30 CN disclosed
CN-101506142-B Process for production of trans-2,2-dimethyl- 3-formylcyclopropane carboxylic acid ester SUMITOMO CO LTD 2013-04-17 CN disclosed
CN-1852887-B Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CO LTD 2012-08-15 CN disclosed
EP-1950208-B1 PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE SUMITOMO CHEMICAL CO (JP) 2012-05-02 EP disclosed
EP-2341042-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-07-06 EP disclosed
CN-101506142-A Process for production of trans-2,2-dimethyl- 3-formylcyclopropane carboxylic acid ester SUMITOMO CHEMICAL CO (JP) 2009-08-12 CN disclosed
EP-2053037-A1 PROCESS FOR PRODUCTION OF TRANS-2,2-DIMETHYL- 3-FORMYLCYCLOPROPANE CARBOXYLIC ACID ESTER Sumitomo Chemical Company, Limited (JP) 2009-04-29 EP disclosed
US-20090048450-A1 Process for production of optically active cyclopropanecarboxylate compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-19 US disclosed
EP-1950208-A1 PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE Sumitomo Chemical Company, Limited (JP) 2008-07-30 EP disclosed
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound SUMITOMO CHEMICAL COMPANY, LIMITED 2008-01-31 US disclosed
EP-1783111-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
EP-1783130-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-08 US disclosed
CN-1852887-A Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CHEMICAL CO (JP) 2006-10-25 CN disclosed
EP-1674445-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND AND ASYMMETRIC COPPER COMPLEX FOR USE IN THE SAME Sumitomo Chemical Company, Limited (JP) 2006-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound ACSL6, AOC1, CA6 LMNA 4253/4885ALDH1A1 1222/4885HSD17B10 1848/4885
US-20090048450-A1 Process for production of optically active cyclopropanecarboxylate compound CBR3, C9, CBR1 LMNA 3700/4885ALDH1A1 1594/4885HSD17B10 1171/4885
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same CBR3, AOC3, CBR1 LMNA 4237/4885ALDH1A1 185/4885HSD17B10 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.