SCHEMBL1150163

SCHEMBL1150163

CCOC(=O)C1C(COC(C)=O)C1(C)C

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.51
ALDH1A1 P00352 8/20 0.45
HSD17B10 Q99714 1/20 0.45
TSHR P16473 3/20 0.34
TP53 P04637 1/20 0.33
MAPT P10636 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTT P42858 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1685649 1.00 LMNA (0.51) LMNAALDH1A1HSD17B10TSHRTP53
SCHEMBL1150166 1.00 LMNA (0.51) LMNAALDH1A1HSD17B10TSHRTP53
SCHEMBL1150168 1.00 LMNA (0.51) LMNAALDH1A1HSD17B10TSHRTP53
SCHEMBL1685648 1.00 LMNA (0.51) LMNAALDH1A1HSD17B10TSHRTP53
SCHEMBL1149828 0.86 ALDH1A1 (0.41) LMNAALDH1A1HSD17B10TSHR
SCHEMBL1150465 0.85 ALDH1A1 (0.53) LMNAALDH1A1HSD17B10TSHRSMN1; SMN2
SCHEMBL1685655 0.84 LMNA (0.46) LMNAALDH1A1TSHRTP53MAPT
SCHEMBL1150190 0.84 LMNA (0.34) LMNAALDH1A1HSD17B10HTT
SCHEMBL1150187 0.83 ALDH1A1 (0.47) LMNAALDH1A1TSHRTP53
SCHEMBL20815360 0.83 LMNA (0.45) LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116135835-B Method for preparing chiral 3-acetoxymethyl-2, 2-dimethylcyclopropane carboxylic ester 中国科学院大连化学物理研究所 2025-02-25 CN claimed
CN-116135835-A Method for preparing chiral 3-acetoxymethyl-2, 2-dimethylcyclopropane carboxylic ester 中国科学院大连化学物理研究所 2023-05-19 CN claimed
CN-117263791-A Method for preparing 3, 3-dimethyl-1, 2-cyclopropane dicarboxylic acid 中国科学院大连化学物理研究所 2023-12-22 CN disclosed
EP-2341042-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND SUMITOMO CHEMICAL CO (JP) 2019-03-20 EP disclosed
EP-1783111-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND SUMITOMO CHEMICAL CO (JP) 2015-04-08 EP disclosed
EP-2781522-A1 OPTICALLY ACTIVE BISOXAZOLINE COMPOUND, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND USING SAID CATALYST Sumitomo Chemical Company, Limited (JP) 2014-09-24 EP disclosed
US-8680328-B2 Method for producing optically active cyclopropane carboxylic acid ester compound, asymmetric copper complex, and optically active salicylideneaminoalcohol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-03-25 US disclosed
EP-1950208-B1 PROCESS FOR PRODUCING 6,6-DIMETHYL-3-OXABICYCLO[3.1.0]HEXAN-2-ONE SUMITOMO CHEMICAL CO (JP) 2012-05-02 EP disclosed
US-20110166372-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-07 US disclosed
EP-2341042-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-07-06 EP disclosed
US-7928253-B2 Method of producing 6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-one SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-19 US disclosed
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound SUMITOMO CHEMICAL COMPANY, LIMITED 2008-01-31 US disclosed
EP-1783111-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
EP-1783130-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANECARBOXYLATE COMPOUND Sumitomo Chemical Company, Limited (JP) 2007-05-09 EP disclosed
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-02-08 US disclosed
EP-1728780-A1 PROCESSES FOR PRODUCING 3-METHYL-2-BUTENYL ACETATE Sumitomo Chemical Company, Limited (JP) 2006-12-06 EP disclosed
EP-1674445-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE COMPOUND AND ASYMMETRIC COPPER COMPLEX FOR USE IN THE SAME Sumitomo Chemical Company, Limited (JP) 2006-06-28 EP disclosed
US-4599358-A Pyrethroids MONTEDISON, S.P.A. (IT) 1986-07-08 US disclosed
EP-0031041-B1 PYRETHROIDS AND THEIR PREPARATION, THEIR PESTICIDAL COMPOSITION; INTERMEDIATES AND THEIR PREPARATION Montedison S.p.A. (IT) 1985-02-13 EP disclosed
EP-0031041-A2 Pyrethroids and their preparation, their pesticidal composition; intermediates and their preparation Montedison S.p.A. (IT) 1981-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166372-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE CYCLOPROPANE CARBOXYLIC ACID ESTER COMPOUND, ASYMMETRIC COPPER COMPLEX, AND OPTICALLY ACTIVE SALICYLIDENEAMINOALCOHOL COMPOUND ALDH18A1, ALDH3A1, DECR1 LMNA 4539/4885ALDH1A1 30/4885HSD17B10 392/4885
US-20080027235-A1 Method for Producing Optically Active Cyclopropanecarboxylate Compound ACSL6, AOC1, CA6 LMNA 4253/4885ALDH1A1 1222/4885HSD17B10 1848/4885
US-20070032659-A1 Process for producing optically active cyclopropane compound and asymmetric copper complex for use in the same CBR3, AOC3, CBR1 LMNA 4237/4885ALDH1A1 185/4885HSD17B10 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.