Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.75 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.75 |
| ▸ | FABP3 | P05413 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314440 | 0.87 | FABP4 (1.00) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL30573159 | 0.87 | FABP4 (1.00) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL354539 | 0.86 | FABP4 (0.64) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL28795573 | 0.82 | KDM4E (0.72) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL27338889 | 0.82 | MAPT (0.62) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL12951764 | 0.82 | FABP4 (1.00) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL6550438 | 0.81 | TDP1 (0.64) | FABP4FABP5KDM4EALDH1A1HPGD | |
| SCHEMBL5999234 | 0.81 | FABP4 (0.78) | FABP4FABP5FABP3CNR2HDAC6 | |
| SCHEMBL6419189 | 0.81 | FABP4 (0.97) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL29114062 | 0.81 | FABP4 (0.97) | FABP4FABP5FABP3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207214-B2 | 3-aminocarbazole compounds, pharmaceutical composition containing the same and method for the preparation thereof | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2012-06-26 | — | — | US | disclosed |
| US-20110046197-A1 | 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCE (IT) | 2011-02-24 | — | — | US | disclosed |
| US-7879900-B2 | Antiinflammatory agents; antitumor agents; Alzheimer's disease;atherosclerosis | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2011-02-01 | — | — | US | disclosed |
| CN-101223139-B | 3-aminocarbazole compound, pharmaceutical composition containing the same, and method for producing the same | ACRAF | 2010-11-17 | — | — | CN | disclosed |
| EP-1910288-B1 | 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF | ACRAF (IT) | 2010-06-23 | — | — | EP | disclosed |
| US-20080207727-A1 | 3-Aminocarbazole Compounds, Pharmaceutical Composition Containing the Same and Method for the Preparation Thereof | AZIENDE CHIMICHE RIUNTE ANGELINI FRANCE (IT) | 2008-08-28 | — | — | US | disclosed |
| CN-101223139-A | 3-aminocarbazole compound, pharmaceutical composition containing the same, and method for producing the same | ACRAF (IT) | 2008-07-16 | — | — | CN | disclosed |
| EP-1910288-A1 | 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007014687-A1 | 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207727-A1 | 3-Aminocarbazole Compounds, Pharmaceutical Composition Containing the Same and Method for the Preparation Thereof | CYP2C19, CYP2C9, CYP3A43 | FABP4 3331/4885FABP5 3089/4885FABP3 3802/4885 |
| US-20110046197-A1 | 3-AMINOCARBAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND METHOD FOR THE PREPARATION THEREOF | IL17A, APC, IL33 | FABP4 943/4885FABP5 1146/4885FABP3 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.