Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135535 | 0.86 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRCYP3A4MAPT | |
| SCHEMBL11330333 | 0.83 | ALDH1A1 (0.42) | ALDH1A1LMNATSHRCYP3A4MAPT | |
| SCHEMBL15624152 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LMNATSHRCYP3A4MAPT | |
| SCHEMBL2137245 | 0.81 | ALDH1A1 (0.41) | ALDH1A1LMNATSHRCYP3A4MAPT | |
| SCHEMBL11169949 | 0.81 | ADRA2A (0.46) | ALDH1A1TSHRMAPTDGKAFNTA | |
| SCHEMBL514195 | 0.81 | TSHR (0.55) | ALDH1A1LMNATSHRMAPTDGKA | |
| SCHEMBL23797438 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNATSHRCYP3A4MAPT | |
| SCHEMBL7557773 | 0.79 | TSHR (0.56) | ALDH1A1TSHRMAPTDGKAHPGD | |
| SCHEMBL11352492 | 0.79 | DGKA (0.52) | ALDH1A1TSHRMAPTDGKAL3MBTL1 | |
| SCHEMBL7860299 | 0.79 | DGKA (0.46) | ALDH1A1LMNATSHRMAPTDGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133813-A | Cyclic nitrile carbonate-containing compounds | ATLANTIC RICHFIELD COMPANY (US) | 1979-01-09 | — | — | US | disclosed |