Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA6 | P23280 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11295491 | 0.76 | MTNR1A (0.36) | MTNR1AMTNR1BHDAC4 | |
| SCHEMBL11472591 | 0.73 | SLC6A4 (0.33) | HDAC4 | |
| SCHEMBL11544999 | 0.70 | AKR1C1 (0.37) | KMT2AHDAC4NPC1 | |
| SCHEMBL11291104 | 0.70 | SMN1; SMN2 (0.42) | MTNR1AMTNR1BKMT2AHDAC4NPC1 | |
| SCHEMBL11294472 | 0.69 | HDAC4 (0.35) | HDAC4 | |
| SCHEMBL11548754 | 0.69 | HDAC4 (0.35) | HDAC4 | |
| SCHEMBL5127639 | 0.69 | LMNA (0.48) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL11295572 | 0.68 | LMNA (0.37) | KMT2AHDAC4 | |
| SCHEMBL31452460 | 0.68 | SLC6A4 (0.34) | KMT2A | |
| SCHEMBL11288858 | 0.68 | SLC6A4 (0.34) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000825-A1 | Geminally disubstituted indene derivatives, processes for their preparation and pharmaceutical compositions containing them | Kabi AB (SE) | 1979-02-21 | — | — | EP | disclosed |