Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 4/20 | 0.33 |
| ▸ | MMP7 | P09237 | 3/20 | 0.33 |
| ▸ | MMP12 | P39900 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11730456 | 0.77 | CNR2 (0.35) | CNR2KIF11PRSS1CTSGCTRB1 | |
| SCHEMBL27433687 | 0.76 | PPARG (0.47) | CNR2KIF11PRSS1CTSGCTRB1 | |
| SCHEMBL9244427 | 0.75 | ALDH1A1 (0.48) | CNR2PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL11340509 | 0.73 | CNR2 (0.33) | CNR2KIF11PRSS1CTSGCTRB1 | |
| SCHEMBL11503528 | 0.73 | CNR2 (0.33) | CNR2KIF11PRSS1CTSGCTRB1 | |
| SCHEMBL4635829 | 0.73 | LTA4H (0.44) | CNR2LTA4HALDH1A1CYP3A4 | |
| SCHEMBL10682475 | 0.72 | CNR2 (0.36) | CNR2KIF11PRSS1CTSGCTRB1 | |
| SCHEMBL4011121 | 0.71 | KIF11 (0.36) | CNR2KIF11PRSS1CTSGCTRB1 | |
| SCHEMBL11503776 | 0.71 | CNR2 (0.31) | CNR2 | |
| SCHEMBL11340341 | 0.71 | CNR2 (0.34) | CNR2KIF11PRSS1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179451-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATOR, ANTICONVULSANTS OR ANTIMICROBIAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | claimed |