Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550765 | 0.86 | TP53 (0.37) | MAOBNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11548529 | 0.85 | TP53 (0.36) | MAOBNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11553593 | 0.82 | ALDH1A1 (0.45) | ALOX15ALOX12ALDH2MAOAMAOB | |
| SCHEMBL11548968 | 0.76 | MAPT (0.47) | MAOAMAOBKDM4ENPC1ALDH1A1 | |
| SCHEMBL11548259 | 0.76 | NISCH (0.50) | MAOAMAOBKDM4ENPC1ALDH1A1 | |
| SCHEMBL11503585 | 0.75 | CA12 (0.40) | MAOAMAOBKDM4ENPC1RAB9A | |
| SCHEMBL10743625 | 0.72 | FTO (0.35) | ALOX15ALOX12ALDH2MAOAMAOB | |
| SCHEMBL11228847 | 0.70 | MAPT (0.40) | ALOX15ALOX12ALDH2MAOAMAOB | |
| SCHEMBL2360039 | 0.68 | KDM4E (0.67) | ALOX15ALOX12ALDH2MAOAMAOB | |
| SCHEMBL11549647 | 0.67 | POLB (0.51) | ALOX15ALOX12KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54059279-A | — | — | None | — | — | JP | disclosed |
| JP-S5459279-A | NOVEL CHROMONE DERIVATIVE AND ITS PREPARATION | TAKEDA CHEM IND LTD | 1979-05-12 | — | — | JP | disclosed |