Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | COMT | P21964 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57009 | 0.81 | POLB (0.57) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL20982453 | 0.79 | RHEB (0.52) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL6061802 | 0.74 | RHEB (0.57) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL416600 | 0.74 | ALDH1A1 (0.74) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL22649095 | 0.73 | NPC1 (0.67) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL20982583 | 0.72 | RHEB (0.70) | KDM4EKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL10761652 | 0.71 | MMP2 (0.52) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL18585800 | 0.71 | NPC1 (0.57) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL31592975 | 0.70 | MMP2 (0.64) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL27825168 | 0.70 | PRMT1 (0.54) | KDM4EKMT2AALDH1A1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150051-A | N-Cyanosulfonamide compounds | CIBA-GEIGY CORPORATION (US) | 1979-04-17 | — | — | US | disclosed |
| US-4080483-A | COATINGS, MOLDING MATERIALS, LAMINATION | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4075185-A | ADDITION POLYMERIZATION | CIBA-GEIGY CORPORATION (US) | 1978-02-21 | — | — | US | disclosed |
| US-4049711-A | POLYSULFONAMIDE MONOMERS | CIBA-GEIGY CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-3944526-A | N-cyanosulfonamide resins and intermediates therefor and products thereof | CIBA-GEIGY CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |