Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | FASN | P49327 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472504 | 0.98 | MEN1 (0.37) | CHRM2CHRM3IDH2KMT2AFASN | |
| SCHEMBL11447045 | 0.85 | CHRM2 (0.40) | CHRM2CHRM3IDH2KMT2AFASN | |
| SCHEMBL11446724 | 0.83 | CHRM2 (0.33) | CHRM2CHRM3IDH2KMT2AFASN | |
| SCHEMBL11330925 | 0.83 | KMT2A (0.39) | CHRM2CHRM3KMT2AFASNMEN1 | |
| SCHEMBL11506608 | 0.82 | CHRM2 (0.44) | CHRM2CHRM3KMT2AFASNMEN1 | |
| SCHEMBL11341621 | 0.82 | TRPM8 (0.32) | CHRM2CHRM3KMT2AFASNMEN1 | |
| SCHEMBL11510578 | 0.81 | CHRM2 (0.38) | CHRM2CHRM3KMT2AFASNMEN1 | |
| SCHEMBL11470164 | 0.79 | MEN1 (0.41) | CHRM2CHRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11465317 | 0.75 | MLYCD (0.40) | CHRM2CHRM3KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11436157 | 0.74 | OPRM1 (0.36) | CHRM2CHRM3IDH2KMT2AFASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156015-A | N-(2-Aminocyclopentyl)acylanilides and treating depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |