Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437980 | 0.77 | OPRM1 (0.36) | OPRM1OPRK1OPRD1ALDH1A1MEN1 | |
| SCHEMBL11447045 | 0.76 | CHRM2 (0.40) | CHRM2CHRM3FASNALDH1A1MEN1 | |
| SCHEMBL11330925 | 0.75 | KMT2A (0.39) | CHRM2CHRM3FASNALDH1A1MEN1 | |
| SCHEMBL11507801 | 0.74 | CHRM2 (0.38) | OPRM1CHRM2CHRM3FASNALDH1A1 | |
| SCHEMBL11472504 | 0.72 | MEN1 (0.37) | CHRM2CHRM3FASNALDH1A1MEN1 | |
| SCHEMBL11443811 | 0.70 | ALDH1A1 (0.39) | OPRM1OPRK1OPRD1CHRM2CHRM3 | |
| SCHEMBL11446778 | 0.70 | OPRM1 (0.38) | OPRM1OPRK1OPRD1CHRM2CHRM3 | |
| SCHEMBL11442496 | 0.69 | CHRM2 (0.37) | OPRM1OPRK1OPRD1CHRM2CHRM3 | |
| SCHEMBL11446724 | 0.67 | CHRM2 (0.33) | CHRM2CHRM3FASNKMT2AIDH2 | |
| SCHEMBL11334445 | 0.67 | KDM4E (0.40) | OPRM1OPRK1OPRD1CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217362-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4212888-A | Anilide derivatives as antidepressants | THE UPJOHN COMPANY (US) | 1980-07-15 | — | — | US | disclosed |