Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17984648 | 0.81 | CYP1A2 (0.50) | GAAKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL11508571 | 0.81 | GAA (0.45) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL29036215 | 0.79 | GAA (0.42) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL30786543 | 0.75 | KMT2A (0.43) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11529393 | 0.75 | HTR1A (0.37) | KMT2AMEN1ALDH1A1PKMTSHR | |
| SCHEMBL23149714 | 0.75 | KMT2A (0.43) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL3400467 | 0.74 | ALDH1A1 (0.44) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL11507652 | 0.73 | P2RX7 (0.50) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL3943579 | 0.71 | P2RX7 (0.54) | GAAMGAMSIMGAM2KMT2A | |
| SCHEMBL8139286 | 0.70 | NPC1 (0.41) | GAAALDH1A1KDM4EPKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145423-A | TREATMENT OF SCHISTOSOMIASIS AND AMOEBIASIS, NEMATODES, ANTIPROTAZOA | RHONE-POULENC INDUSTRIES (FR) | 1979-03-20 | — | — | US | disclosed |
| US-4104386-A | Derivatives of 1,2-dithiole and anti-bilharzia compositions thereof | RHONE-POULENC INDUSTRIES (FR) | 1978-08-01 | — | — | US | disclosed |