Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770963 | 1.00 | ESR1 (0.51) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL27931292 | 0.87 | TUBB4A (0.64) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL23203427 | 0.82 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL5804721 | 0.82 | MAPT (0.52) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| Nudol SCHEMBL3971615 | 0.81 | TUBB4A (0.54) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL9623295 | 0.79 | ESR1 (0.55) | ESR1ESR2KDM4EMAPTMAOA | |
| SCHEMBL23203412 | 0.79 | TUBB4A (0.51) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL11508300 | 0.77 | MCL1 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28891976 | 0.76 | CYP1A2 (0.46) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL9623607 | 0.73 | ESR1 (0.75) | ESR1ESR2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113403362-A | Method for detecting effect of 1,5, 6-trimethoxy-2, 7-dihydroxyphenanthrene on HepG-2 cells and application | 沈阳药科大学 | 2021-09-17 | — | — | CN | claimed |
| CN-113384564-A | Application of p53 target-based trimethoxy dihydroxy phenanthrene compound in cervical cancer resistance and detection method | 沈阳药科大学 | 2021-09-14 | — | — | CN | claimed |
| CN-112870186-A | Medicine for treating or preventing human liver cancer and preparation method and application thereof | 沈阳药科大学 | 2021-06-01 | — | — | CN | claimed |
| CN-112870185-A | Medicine for treating or preventing cervical cancer of human, preparation method and application | 沈阳药科大学 | 2021-06-01 | — | — | CN | claimed |
| CN-113403362-A | Method for detecting effect of 1,5, 6-trimethoxy-2, 7-dihydroxyphenanthrene on HepG-2 cells and application | 沈阳药科大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-113403362-A | Method for detecting effect of 1,5, 6-trimethoxy-2, 7-dihydroxyphenanthrene on HepG-2 cells and application | 沈阳药科大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-113403362-A | Method for detecting effect of 1,5, 6-trimethoxy-2, 7-dihydroxyphenanthrene on HepG-2 cells and application | 沈阳药科大学 | 2021-09-17 | — | — | CN | disclosed |
| CN-113384564-A | Application of p53 target-based trimethoxy dihydroxy phenanthrene compound in cervical cancer resistance and detection method | 沈阳药科大学 | 2021-09-14 | — | — | CN | disclosed |
| CN-113384564-A | Application of p53 target-based trimethoxy dihydroxy phenanthrene compound in cervical cancer resistance and detection method | 沈阳药科大学 | 2021-09-14 | — | — | CN | disclosed |
| CN-112870186-A | Medicine for treating or preventing human liver cancer and preparation method and application thereof | 沈阳药科大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-112870185-A | Medicine for treating or preventing cervical cancer of human, preparation method and application | 沈阳药科大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-112870186-A | Medicine for treating or preventing human liver cancer and preparation method and application thereof | 沈阳药科大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-112870185-A | Medicine for treating or preventing cervical cancer of human, preparation method and application | 沈阳药科大学 | 2021-06-01 | — | — | CN | disclosed |
| CN-103265414-A | Preparation method of confusarin | NANJING ZELANG MEDICAL TECH CO | 2013-08-28 | — | — | CN | disclosed |
| WO-2006089881-A1 | USE OF PHENANTHRENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS, SYNTHESIS METHOD AND INTERMEDIATE PRODUCTS | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2006-08-31 | — | — | WO | disclosed |