SCHEMBL11508564

SCHEMBL11508564

CN(C)c1ccccc1N(C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.54
MAPT P10636 3/20 0.54
ALDH1A1 P00352 3/20 0.54
TSHR P16473 2/20 0.54
TP53 P04637 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
HTR6 P50406 1/20 0.42
TSPO P30536 1/20 0.42
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
HPGD P15428 1/20 0.41
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
NSD2 O96028 1/20 0.38
EGFR P00533 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6469191 0.82 CXCR2 (0.44) GAAMAPTALDH1A1TSHRTP53
SCHEMBL15224071 0.82 TSPO (0.55) GAAMAPTALDH1A1TSHRTP53
Benzene SCHEMBL28335658 0.80 TRPM8 (0.50) ALDH1A1LMNAKMT2A
SCHEMBL1029152 0.80 TRPM8 (0.50) ALDH1A1LMNAKMT2A
SCHEMBL2091489 0.78 DDB1 (0.47) GAAMAPTALDH1A1TSHRTP53
SCHEMBL1838817 0.78 MAPK13 (0.41) GAAMAPTALDH1A1TSHRTP53
SCHEMBL31314405 0.78 MAPK13 (0.41) GAAMAPTALDH1A1TSHRTP53
SCHEMBL2092009 0.78 CA12 (0.41) GAAMAPTALDH1A1TSHRTP53
SCHEMBL1046327 0.78 ALDH1A1 (0.52) GAAMAPTALDH1A1TSHRTP53
SCHEMBL6219691 0.78 HPGD (0.46) GAAMAPTALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4172146-A Substituted phenyl derivatives CIBA-GEIGY CORPORATION (US) 1979-10-23 US disclosed
US-4153604-A INSECTICIDES CIBA-GEIGY CORPORATION (US) 1979-05-08 US disclosed
US-4069344-A INSECTICIDAL SUBSTITUTED PHENYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed
US-4067972-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4058604-A OR ACARICIDALLY ACTIVE SUBSTANCES CIBA-GEIGY AG (CH) 1977-11-15 US disclosed
US-4035488-A Insecticidal and acaricidal substituted phenyl thiophosphoric acid esters CIBA-GEIGY CORPORATION (US) 1977-07-12 US disclosed
US-4017563-A INSECTICIDES, REDUCED TOXICITY TO MAMMALS CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4003964-A ACARICIDES, INSECTICIDES, NEMATOCIDES CIBA-GEIGY AG (CH) 1977-01-18 US disclosed
US-3998855-A INSECTICIDES CIBA-GEIGY CORPORATION (US) 1976-12-21 US disclosed
US-3991140-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1976-11-09 US disclosed
US-3966921-A NEMATOCIDES CIBA-GEIGY CORPORATION (US) 1976-06-29 US disclosed
US-3956306-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3948940-A Pesticidal phthalimido phosphorous ester compounds CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3941829-A PESTICIDE CIBA-GEIGY CORPORATION (US) 1976-03-02 US disclosed
US-3940412-A 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them CIBA-GEIGY AG (CH) 1976-02-24 US disclosed
US-3935224-A 4H-Pyrido[3,2a]-1,3,2-dioxophosphorane derivatives CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3933945-A O-ethyl-S-(n)propyl-S-diallylcarbmoylmethyldithiophosphate CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932629-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932630-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed