Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 3/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115199 | 0.86 | HPGD (0.44) | F7F3BRD4BRD9ALDH1A1 | |
| SCHEMBL115047 | 0.85 | METAP2 (0.43) | F7F3BRD4LMNAHPGD | |
| SCHEMBL115064 | 0.82 | F7 (0.39) | F7F3BRD4BRD9GRM4 | |
| SCHEMBL115125 | 0.82 | TP53 (0.39) | F7F3BRD4BRD9GRM4 | |
| SCHEMBL115231 | 0.82 | F7 (0.44) | F7F3BRD4BRD9GRM4 | |
| SCHEMBL113668 | 0.79 | CASR (0.38) | BRD4GRM4ALDH1A1ALDH1A3CASR | |
| SCHEMBL114965 | 0.75 | KCNA3 (0.35) | BRD4ALDH1A1HPGDTACR1KCNA3 | |
| SCHEMBL115043 | 0.75 | ERCC1 (0.39) | BRD4ALDH1A1HPGDCASRTACR1 | |
| SCHEMBL115298 | 0.75 | METAP2 (0.35) | BRD4ALDH1A1HPGDCASRKCNA3 | |
| SCHEMBL114971 | 0.74 | PDE10A (0.35) | BRD4GRM4ALDH1A1ALDH1A3CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | F7 3305/4885F3 4126/4885BRD4 3524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.