Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 5/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113740 | 0.86 | KDM4E (0.42) | CNR2CNR1BRD4CASRALDH1A1 | |
| SCHEMBL115108 | 0.84 | METAP2 (0.43) | — | |
| SCHEMBL113668 | 0.82 | CASR (0.38) | BRD4CASRALDH1A2ALDH1A1ALDH1A3 | |
| SCHEMBL116012 | 0.82 | ADORA3 (0.36) | CNR2CNR1BRD4CASR | |
| SCHEMBL115124 | 0.82 | LMNA (0.40) | BRD4ALDH1A1GRM4ELANE | |
| SCHEMBL115125 | 0.79 | TP53 (0.39) | BRD4CASRGRM4 | |
| SCHEMBL115145 | 0.77 | CASR (0.33) | PDE10APDE2ABRD4CASRGRM4 | |
| SCHEMBL115021 | 0.77 | CASR (0.33) | PDE10APDE2ABRD4CASRALDH1A1 | |
| SCHEMBL114970 | 0.76 | CASR (0.34) | PDE10APDE2ABRD4CASRELANE | |
| SCHEMBL113677 | 0.76 | KCNA3 (0.32) | PDE10APDE2ABRD4CASRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | PDE10A 2605/4885PDE2A 1769/4885CNR2 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.