SCHEMBL9742985

SCHEMBL9742985

CCCCCCCCCCCCCCCCSc1ccncc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.46
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
NAAA Q02083 1/20 0.41
MAPT P10636 1/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
PLK1 P53350 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
NPC1 O15118 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743357 1.00 GPR84 (0.46) GPR84THRATHRBCYP3A4CYP2D6
SCHEMBL424824 0.92 MAOA (0.49) CYP3A4CYP2D6CYP1A2CYP2C9CYP2C19
SCHEMBL8966315 0.90 KDM4E (0.47) GPR84THRATHRBCYP3A4CYP2D6
SCHEMBL8966863 0.90 KDM4E (0.47) GPR84THRATHRBCYP3A4CYP2D6
SCHEMBL8966693 0.90 KDM4E (0.47) GPR84THRATHRBCYP3A4CYP2D6
SCHEMBL8967318 0.86 NAAA (0.45) GPR84THRATHRBCYP3A4CYP2D6
SCHEMBL8966742 0.86 NAAA (0.45) GPR84THRATHRBCYP3A4CYP2D6
SCHEMBL21575599 0.85 THRB (0.56) GPR84THRATHRBMAOAMAOB
SCHEMBL21575598 0.85 THRB (0.56) GPR84THRATHRBMAOAMAOB
SCHEMBL11569857 0.85 THRB (0.56) GPR84THRATHRBMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5132093-A SYNERGISTIC CORROSION INHIBITORS BASED ON SUBSTITUTED PYRIDINIUM COMPOUNDS SRI INTERNATIONAL (US) 1992-07-21 US disclosed
WO-1990001478-A1 SYNERGISTIC CORROSION INHIBITORS BASED ON SUBSTITUTED PYRIDINIUM COMPOUNDS SRI INTERNATIONAL (US) 1990-02-22 WO disclosed