SCHEMBL11510322

SCHEMBL11510322

C#CCN(CC)c1ccccc1OC(=O)NC

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
PGR P06401 1/20 0.47
GAA P10253 1/20 0.47
PTGS1 P23219 1/20 0.47
MAPK1 P28482 1/20 0.47
HSD17B10 Q99714 1/20 0.47
ACHE P22303 6/20 0.43
MAOA P21397 3/20 0.39
MAOB P27338 3/20 0.39
BCHE P06276 2/20 0.39
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11689574 0.93 ALDH1A1 (0.50) ALDH1A1PGRGAAPTGS1MAPK1
Iodomethane SCHEMBL7648113 0.85 ALDH1A1 (0.49) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL435129 0.84 ACHE (0.46) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL31741648 0.84 ACHE (0.46) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL11511623 0.74 ALDH1A1 (0.47) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL11508565 0.74 ALDH1A1 (0.56) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL11584707 0.72 ALDH1A1 (0.50) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL5566341 0.72 ALDH1A1 (0.54) ALDH1A1PGRGAAPTGS1MAPK1
SCHEMBL11510318 0.71 MAOA (0.42) ALDH1A1ACHEMAOAMAOBLMNA
SCHEMBL11509648 0.69 ACHE (0.41) ALDH1A1ACHEMAOAMAOBBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4172146-A Substituted phenyl derivatives CIBA-GEIGY CORPORATION (US) 1979-10-23 US disclosed
US-4153604-A INSECTICIDES CIBA-GEIGY CORPORATION (US) 1979-05-08 US disclosed
US-4069344-A INSECTICIDAL SUBSTITUTED PHENYL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed
US-4067972-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1978-01-10 US disclosed
US-4058604-A OR ACARICIDALLY ACTIVE SUBSTANCES CIBA-GEIGY AG (CH) 1977-11-15 US disclosed
US-4035488-A Insecticidal and acaricidal substituted phenyl thiophosphoric acid esters CIBA-GEIGY CORPORATION (US) 1977-07-12 US disclosed
US-4017563-A INSECTICIDES, REDUCED TOXICITY TO MAMMALS CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4006229-A Insecticidal and acaricidal trihalophenyl thiophosphates CIBA-GEIGY AG (CH) 1977-02-01 US disclosed
US-4003964-A ACARICIDES, INSECTICIDES, NEMATOCIDES CIBA-GEIGY AG (CH) 1977-01-18 US disclosed
US-3998855-A INSECTICIDES CIBA-GEIGY CORPORATION (US) 1976-12-21 US disclosed
US-3956306-A PESTICIDES CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3948940-A Pesticidal phthalimido phosphorous ester compounds CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3941829-A PESTICIDE CIBA-GEIGY CORPORATION (US) 1976-03-02 US disclosed
US-3940412-A 2,4,5-Trichloro- and 2,4,5-tribromoimidazole derivatives and pesticidal compositions containing them CIBA-GEIGY AG (CH) 1976-02-24 US disclosed
US-3935224-A 4H-Pyrido[3,2a]-1,3,2-dioxophosphorane derivatives CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3934010-A MITICIDE CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3933945-A O-ethyl-S-(n)propyl-S-diallylcarbmoylmethyldithiophosphate CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3932630-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932629-A Triazolyl phosphorus esters as pesticides CIBA-GEIGY CORPORATION (US) 1976-01-13 US disclosed
US-3932632-A Insecticidal compositions containing an organophosphorus compound and a thiolcarbamate BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-01-13 US disclosed