Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11004620 | 0.91 | GAA (0.41) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL11511671 | 0.84 | VCAM1 (0.43) | ALDH1A1GAAMAPTTHRBPOLB | |
| SCHEMBL574218 | 0.83 | HPGD (0.45) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL574219 | 0.83 | HPGD (0.45) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL10222901 | 0.81 | HPGD (0.43) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL574175 | 0.81 | HPGD (0.43) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL573731 | 0.81 | HPGD (0.43) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL22922726 | 0.80 | KDM4E (0.42) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL11512332 | 0.80 | KDM4E (0.42) | ALDH1A1HPGDKDM4EGAAPKM | |
| SCHEMBL572903 | 0.79 | KDM4E (0.38) | ALDH1A1HPGDKDM4EGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172142-A | DIURETICS FOR TREATMENT OF EDEMA | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |