Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510885 | 0.91 | MAPT (0.43) | VCAM1MEN1KMT2AMAPTGAA | |
| SCHEMBL573280 | 0.84 | VCAM1 (0.45) | VCAM1MEN1KMT2AMAPTGAA | |
| SCHEMBL573281 | 0.84 | VCAM1 (0.45) | VCAM1MEN1KMT2AMAPTGAA | |
| SCHEMBL11510618 | 0.84 | ALDH1A1 (0.43) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL574029 | 0.83 | VCAM1 (0.46) | VCAM1MEN1KMT2AMAPTGAA | |
| SCHEMBL573657 | 0.83 | VCAM1 (0.46) | VCAM1MEN1KMT2AMAPTGAA | |
| SCHEMBL10222900 | 0.83 | VCAM1 (0.46) | VCAM1MEN1KMT2AMAPTGAA | |
| SCHEMBL21437398 | 0.82 | MAPT (0.43) | VCAM1MEN1KMT2AMAPTGAA | |
| SCHEMBL11543240 | 0.82 | MAPT (0.43) | VCAM1MEN1KMT2AMAPTGAA | |
| SCHEMBL21436556 | 0.81 | VCAM1 (0.50) | VCAM1MEN1KMT2AAKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172142-A | DIURETICS FOR TREATMENT OF EDEMA | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-23 | — | — | US | disclosed |