Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.78 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | SHBG | P04278 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.66 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.66 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.65 |
| ▸ | AR | P10275 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510735 | 1.00 | LMNA (0.78) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL13517611 | 0.88 | LMNA (0.80) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL22761988 | 0.88 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL15445000 | 0.88 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL4877448 | 0.88 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL13518184 | 0.88 | LMNA (0.80) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL13069287 | 0.88 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL13517612 | 0.88 | LMNA (0.80) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL37494 | 0.88 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A | |
| SCHEMBL27035399 | 0.88 | LMNA (1.00) | LMNANR3C1HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177269-A | ANTITUMOR AGENTS | AKTIEBOLAGET LEO (SE) | 1979-12-04 | — | — | US | disclosed |