Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511733 | 0.89 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2TSHRTHRB | |
| SCHEMBL11509020 | 0.88 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2TSHRTHRB | |
| SCHEMBL11512015 | 0.88 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2TSHRTHRB | |
| SCHEMBL11509308 | 0.85 | NLRP3 (0.53) | NPC1RAB9ASMN1; SMN2THRBLMNA | |
| SCHEMBL11510166 | 0.83 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2TSHRTHRB | |
| SCHEMBL7056940 | 0.83 | TGM2 (0.54) | NPC1RAB9ASMN1; SMN2TSHRTHRB | |
| SCHEMBL3203115 | 0.83 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2TSHRTHRB | |
| SCHEMBL14085640 | 0.82 | BCHE (0.47) | NPC1RAB9ASMN1; SMN2TSHRTHRB | |
| SCHEMBL17107937 | 0.82 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2TSHRTHRB | |
| SCHEMBL23463468 | 0.81 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180673-A | USED FOR TRANSFER TAPES IN PRODUCTION OF PRINTED CIRCUITS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1979-12-25 | — | — | US | disclosed |