Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2929137 | 0.82 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL11512223 | 0.78 | SMN1; SMN2 (0.57) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL11525238 | 0.78 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL11638101 | 0.78 | ALDH1A1 (0.59) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL11513173 | 0.77 | CA1 (0.54) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL11325575 | 0.76 | LMNA (0.67) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL11521917 | 0.76 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL14211024 | 0.76 | KMT2A (0.58) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL8718043 | 0.74 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1RAB9AMAPT | |
| SCHEMBL3164500 | 0.74 | ALDH1A1 (0.66) | KMT2AMEN1ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161540-A | SUBSTITUTED ANILIDE | SCHERING CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-4144270-A | NITRO OR HALOGEN SUBSTITUTED CARBOCYCLIC AMIDES | SCHERING CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4139638-A | NITRO OR HALOGEN SUBSTITUTED ANILIDES, ANTIANDROGENS, ACNE, CANCER | SCHERING CORPORATION (US) | 1979-02-13 | — | — | US | disclosed |
| US-3995060-A | SUBSTITUTED ANILIDES | SCHERING CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |