Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CES2 | O00748 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.67 |
| ▸ | AR | P10275 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | AADAC | P22760 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11312186 | 0.88 | ALDH1A1 (0.70) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL11315093 | 0.84 | LMNA (0.69) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL11311655 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL15703102 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL11569517 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL11310805 | 0.84 | ALDH1A1 (0.65) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL3164500 | 0.83 | ALDH1A1 (0.66) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL11314343 | 0.82 | ALDH1A1 (0.64) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL11512455 | 0.81 | ALDH1A1 (0.62) | LMNAALDH1A1SMN1; SMN2MAPK1HTT | |
| SCHEMBL9693251 | 0.81 | ALDH1A1 (0.62) | LMNAALDH1A1SMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170306303-A1 | CONDITIONALLY ACTIVE HETERODIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-10-26 | — | — | US | disclosed |
| US-20170216332-A1 | SMALL MOLECULE ANTI-SCARRING AGENTS | UNIVERSITY OF ROCHESTER (US) | 2017-08-03 | — | — | US | disclosed |
| US-20150057452-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | CATYLIX, INC. (US) | 2015-02-26 | — | — | US | disclosed |
| US-8766006-B2 | Use of nitroaniline derivatives for the production of nitric oxide | STMICROELECTRONICS S.R.L. (IT) | 2014-07-01 | — | — | US | disclosed |
| US-20130224083-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | STMICROELECTRONICS S.R.I. (IT) | 2013-08-29 | — | — | US | disclosed |
| US-4302599-A | Process for nitrating anilides | SCHERING CORPORATION (US) | 1981-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216332-A1 | SMALL MOLECULE ANTI-SCARRING AGENTS | COLGALT1, MMP1, FIBP | LMNA 3382/4885ALDH1A1 970/4885SMN1; SMN2 2316/4885 |
| US-20130224083-A1 | USE OF NITROANILINE DERIVATIVES FOR THE PRODUCTION OF NITRIC OXIDE | NOS2, NOS1, NOS3 | LMNA 2667/4885ALDH1A1 378/4885SMN1; SMN2 3394/4885 |
| US-20150057452-A1 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | LMNA 4227/4885ALDH1A1 1680/4885SMN1; SMN2 4622/4885 |
| US-20170306303-A1 | CONDITIONALLY ACTIVE HETERODIMERIC POLYPEPTIDES AND METHODS OF USE THEREOF | CPB2, AGBL2, IAPP | LMNA 3831/4885ALDH1A1 4013/4885SMN1; SMN2 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.