Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11510029 | 0.85 | ALDH1A1 (0.52) | ALDH1A1MEN1KMT2ANPSR1CYP19A1 | |
| SCHEMBL11513658 | 0.82 | NPC1 (0.51) | NPC1ALDH1A1CYP19A1 | |
| SCHEMBL11511319 | 0.82 | ALDH1A1 (0.51) | NPC1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10480378 | 0.80 | NPC1 (0.56) | NPC1ALDH1A1CYP19A1 | |
| SCHEMBL10480375 | 0.80 | NPC1 (0.56) | NPC1ALDH1A1CYP19A1 | |
| SCHEMBL11511071 | 0.79 | KDM4E (0.57) | NPC1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL9402219 | 0.79 | — | — | |
| SCHEMBL11512754 | 0.78 | KDM4E (0.56) | NPC1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL10480361 | 0.78 | NPC1 (0.54) | NPC1ALDH1A1CYP19A1 | |
| SCHEMBL9402239 | 0.75 | ALDH1A1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |