Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511765 | 0.85 | NPC1 (0.53) | ALDH1A1KMT2AMEN1NPSR1CYP19A1 | |
| SCHEMBL11511071 | 0.83 | KDM4E (0.57) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL11512754 | 0.82 | KDM4E (0.56) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL6403164 | 0.80 | LMNA (0.65) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL10432414 | 0.76 | OPRK1 (0.64) | ALDH1A1KMT2AMEN1KDM4EGAA | |
| SCHEMBL4735710 | 0.75 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL9504656 | 0.74 | KDM4E (0.60) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL11512132 | 0.72 | DRD2 (0.78) | ALDH1A1KMT2AMEN1NPSR1LMNA | |
| SCHEMBL4204712 | 0.72 | MEN1 (0.72) | ALDH1A1KMT2AMEN1KDM4ENPSR1 | |
| SCHEMBL6406874 | 0.71 | LMNA (0.65) | ALDH1A1KMT2AMEN1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178253-A | 1,2,4-TRIAZOLE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1979-12-11 | — | — | US | disclosed |